If for some reason (e.g. when synchronization no longer works properly), you can completely clear and reset OneDrive for Business in a few easy steps.

First, close down all Office programs (such as Word, Excel, Outlook, etc.). Next, open Windows Task Manager, look for and kill these processes:

MSOSYNC.EXE

GROOVE.EXE

MSOUC.EXE

I've noticed that sometimes, these processes get restarted automatically, so be sure they are gone before performing the next step.

Next, locate and delete these folders and their contents:

%LOCALAPPDATA%\Microsoft\Office\Spw

%LOCALAPPDATA%\Microsoft\Office\15.0\OfficeFileCache

If needed, also delete the local copy of all synced libraries. The location depends   ...